营销与写作

pathogen-variant-surveillance

k-dense-ai/scie…t-skills

Queries public GenSpectrum LAPIS data for pathogen genomic surveillance, current lineage nomenclature, weekly sequence proportions, reporting delays, and descriptive mutation frequencies. Use for variant surveillance, Pango lineage validation, dominant submitted lineages, Nextclade assignment provenance, SARS-CoV-2, influenza/H5N1 clades, RSV, mpox, measles, dengue, or LAPIS queries. Distinguishes sequence prevalence from infection prevalence, clades from genotypes, missing calls from reference matches, and sampling changes from biological growth advantage.

  • 978 次安装
  • 5.5万 星标
  • 收录于

安装命令

npx skills add https://github.com/k-dense-ai/scientific-agent-skills --skill pathogen-variant-surveillance

SKILL.md

Pathogen Variant Surveillance

When to use

Use current data when a question depends on which lineages appear in submitted sequences, what a lineage name currently means, or how the submitted sequence distribution changed. Never answer a current circulation question from remembered lineage names or old examples.

This skill supports descriptive surveillance research. Counts describe sequences submitted to one database under stated filters; they are not case counts, infection prevalence, clinical interpretations, outbreak recommendations, or evidence of enhanced pathogen function.

Verified scope

Reviewed on 2026-10-01 against official documentation, live schemas for all 15 registered instances, and small public queries. SARS-CoV-2 served LAPIS 0.8.7/SILO 0.14.3; the other registered deployments served LAPIS 0.8.0/SILO 0.11.0. Do not assume identical feature support. Bundled standard-library scripts have synthetic regression tests and bounded live smoke checks. Nextclade, GenoFLU, authenticated APIs, and sequence-level assay validation are not executed here.